| 中文名称 |
N-[2-(7-甲氧基-1-萘基)乙基]乙酰胺 |
| 英文名称 |
S-20098;N-[2-(7-Methoxy-1-naphthalenyl)ethyl]-acetamide |
| CAS识别号 |
138112-76-2 |
| MDL识别号 |
MFCD00916659 |
| EC识别号 |
Null,without related properties. |
| Beilstein |
Null,without related properties. |
| 分子式 |
C15H17NO2 |
| 分子量 |
243.30 |
| 分子结构图 |
 |
| 产品性状 |
经Bellancom Sciences独家专利技术精制而成，符合《中华人民共和国药典》、USP、EP、JP等相关质量标准。 |
| 质量标准 |
Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant. Agomelatine is an antidepressant drug. |
| 储存条件 |
2-8 °C 冷藏保存，Stored at -2-8 °C |
| 包装说明 |
Bellancom原装进口,正品保证,Bellancom Chemistry The original. |
| 购买建议 |
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